"We have been very impressed with the speed and thoroughness of the Human Microbe Identification Microarray core at the Forsyth Institute. They have been very approachable and professional and the technique confirmed microbial differences seen in samples from different sites in the mouth."
Suzi Adams, Ph.D.
Unilever R&D Port Sunlight
Bebington, United Kingdom
"Oral inflammation is a key component of many intestinal inflammatory disorders, including Crohn’s disease. We would like to thank you for applying the novel HOMIM technology, and for how incredibly easy it is to collaborate with your laboratory. By identifying which microbes may trigger intestinal inflammation, we hope to develop novel approaches to the treatment of inflammatory bowel disease, a serious illness that affects over 1 million Americans."
Athos Bousvaros, MD, MPH
Associate Director, Inflammatory Bowel Disease Center
Associate Professor of Pediatrics, Harvard Medical School
"As a new investigator studying oral pathogenesis associated with HIV-1 infection, I have recently begun using HOMIM-based analyses to identify alterations in oral bacterial populations that occur at different stages of disease progression in untreated patients as well as those on Highly Active Anti-retroviral Therapy (HAART). In our preliminary experiments, HOMIM analyses have consistently provided an extremely detailed and thorough snapshot of the bacterial species residing on the tongue epithelium, and the platform has already allowed us to identify several potentially important changes in the microbiome of HIV infected patients. The turnaround is quick, and the price is reasonable, especially for those of us just starting out. We are enthusiastically looking forward to expanding our collaborative studies with Dr. Paster’s group at the Forsyth Institute."
Michael D. George, Ph.D.
University of California Davis School of Medicine
"From our HOMIM results, we are so excited and satisfied, not only for the nice service and data, but also for your considerate analysis and constructive suggestions. More importantly, we have made some interesting conclusions, e.g., S. mutans is not necessarily involved in dental caries initiation, which was not consistent with our primary expectation. With your cooperation and help, our preliminary results are so very promising and we have decided to further our collaboration and continue utilizing your HOMIM detection assay."
Professor De-qin Yang
The Affiliated Hospital of Stomatology, The Stomatological College
Chongqing Medical University, P.R. China
"In our ongoing studies, HOMIM has shown its great potential for detecting a wide range of different bacteria from periodontal samples. My reasons for choosing this analysis were many. First, the well-documented extensive and long-term scientific work behind HOMIM development gives me the validity I highly appreciate; second, HOMIM has given at least some relief to my frustration coming from the awareness that most bacteria remain uncultivated in periodontal samples and that other practical molecular methods are restricted in their capacity to find uncultivated bacteria or to detect simultaneously many different bacterial species. Third, to get a comprehensive analysis of a complex bacterial population rapidly, meaning really in a couple of weeks, and from numerous samples is a huge step forward to better understand the composition of the microbiota in this unique ecological niche. For our purposes, a very successful modification has been that we prepare and amplify the DNA samples using Dr. Paster’s protocols and then send the amplified samples for HOMIM analysis. Consequently, we have been able to save valuable clinical material for different types of molecular biological analyses."
Sirkka Asikainen, PhD, DDS
Professor and Chair of Oral Microbiology
Umea University, Umea, Sweden
"The HOMIM profiles from Forsyth Institute have taken my oral biofilm research to a whole new level of precision and accuracy. They are easy to implement and are dramatically expanding our understanding of dental caries. The individuals at Forsyth have been extremely responsive and helpful. Thank you!"
V. Kim Kutsch, DMD
CEO, Oral BioTech
"We find that HOMIM is a high-throughput technology very applicable for molecular microbiology. Compared to other methods, it is quick, costs less and is more effective. Our preliminary HOMIM study on microbial analysis of root caries in the elderly won the Hatton Award at the IADR Pan European Federation Conference in London in September, 2008, and is now recently published. HOMIM allowed the analysis of a higher number of subjects than the 16S rRNA gene sequencing method, enabling a statistical evaluation of our findings. At the same time, HOMIM served as a quality and verification control for sequence data."
Professor Ingar Olsen, DDS
University of Oslo, Norway
Your comments and testimonials help to improve HOMIM and our service. Please send your feedback to Dr. Paster at firstname.lastname@example.org