Forsyth MIM
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HOMIM BACTERIAL SPECIES SAMPLE PREPARATION PROTOCOL BACKGROUND DATA OUTPUT REPRODUCIBILITY ANALYSIS REPRODUCIBILITY PROTOCOL The Forsyth Institute Offers New State-of-the-Art Technology
for Bacterial Detection and Identification

In January 2008, Forsyth Microbial Identification Microarray service (MIM) at The Forsyth Institute launched a one-of-a-kind core service to enable the rapid determination of bacterial profiles of clinical samples. The first MIM offering focuses on the detection of bacterial profiles from clinical samples from the oral cavity. Drs. Bruce Paster and Floyd Dewhirst have used molecular analyses based on 16S rRNA sequencing to identify 550 oral bacterial species, of which over half have not yet been cultivated. Using this information, they have developed the Human Oral Microbe Identification Microarray, or HOMIM, which allows the simultaneous detection of about 300 of the most prevalent oral bacterial species, including those that cannot yet be grown in vitro.

The service is fully customizable and can be used to:
- Compare bacterial associations in health vs. disease
- Monitor the effects of therapy on the oral ecology
- Perform microbial perturbation studies

To learn more about this service, please contact Dr. Bruce Paster at 617-892-8288 (bpaster@forsyth.org) or Susan Boches at 617-892-8452 (sboches@forsyth.org). The service will also be available online at bioinformatics.forsyth.org/homim.

This service is available to researchers from academic institutions and industry. Researchers submit DNA isolated from clinical samples and receive an online comprehensive analysis. Depending upon the number of samples to be analyzed and position in the queue, results can usually be obtained within days. Note that results are for research purposes only, and not for diagnostic use.