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HOMIM

HOMIM results have been obtained from clinical samples from many human oral sites, including supragingival and subgingival plaque, the palate, buccal mucosa, vestibule, tongue dorsum, saliva, and lateral tongue surface. Sensitivity is about 0.1% and the limit of detection is about 104 cells.

Examples

  1. Subgingival plaque. HOMIM of a healthy site (A) from a periodontally healthy subject and a diseased site (B) from periodontitis subject. Differences in microbial profiles are readily apparent. Note that the profile from the diseased site is far more complex than the healthy site.
    Subgingival Plaque 1Subgingival Plaque 2
  2. Subgingival plaque from different sites in a single mouth. Microbial profiles of subgingival plaque from the same site are similar (A & B). Microbial profile from an adjacent site (C) has some variation as noted by spots highlighted (boxes).Subgingival Plaque 3