WHAT'S NEW!

Interruption of service. MIM will be moving to a new facility located at 245 First Street in Cambridge, Mass. Consequently, there will be an interuption of services from August 20 to September 13, 2010.

All data are MIAME compliant, which is a requirement for publication in some journals. If requested, HOMIM data will be deposited in a MIAME compliant database, such as GEO.

HOMIM data can be analyzed using many statistical methods. As an example, correspondence analysis (CA) was used to provide a graphic method of examining the relationship of entire microbial profiles with respect to site characteristics (e.g., health and disease, pocket depth).

HOMIM recognition. HOMIMs are presently used in ongoing studies at The Forsyth Institute (6 PIs) and in other national and international collaborations with academic institutions (33 investigators or teams), government including NIH (6 investigative teams), and industry (9 companies).  From these studies using HOMIM, there are presently 3 peer-reviewed publications, 2 have been submitted, 3 reviews describing HOMIM and many presentations at international meetings.

HOMIM publication on determining the bacteria associated with refractory periodontitis by Colombo et al. (2009)--a culmination of our five year study. This reference and Preza et al. (2009a) have detailed descriptions of HOMIM.

People in the lab.

HOMIM has utility beyond determining bacterial associations in oral health and oral diseases. Specific oral bacterial species, bacterial complexes, or entire oral microbial profiles, as determined from HOMIM analyses, may serve as potential biomarkers for non-oral systemic diseases, such as pancreatic cancer, Crohn's Disease and heart disease.